Regulation of Glutamate Dehydrogenases in nit-2 and am Mutants of Neurospora crassa
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چکیده
منابع مشابه
Mutants of NEUROSPORA CRASSA Permeable to Histidinol.
I N Neurospora, L-histidinol is the immediate precursor of L-histidine, as shown by the isolation of L-histidinol dehydrogenase and the study of its catalytic functions (AMES 1957; CREASER, BENNETT and DRYSDALE 1965). The failure of histidine mutants, with the histidinol dehydrogenase function intact, to grow on histidinol, suggests that histidinol cannot enter the cell. However, CATCHESIDE ( 1...
متن کاملUltraviolet-sensitive mutants in Neurospora crassa.
ADIATION-SENSITIVE mutants in bacteria have been reported repeatedly in recent years (s,ee SETLOW 1966). Several loci concerned with sensitivity have been mapped. Some of these mutants not only lacked the ability to repair damaged DNA but also failed to undergo genetic recombination (CLARK and MARGULIES 1965; HOWARD-FLANDERS and THERIOT 1966; VAN DE PUTTE et al. 1966). Among the eucaryotic orga...
متن کاملMutants affecting thymidine metabolism in Neurospora crassa.
When (14)C-thymidine labeled only in the ring is administered to Neurospora crassa, the majority of the recovered label is found in the ribonucleic acid (RNA). Three mutants were isolated in which different steps are blocked in the pathway that converts the pyrimidine ring of thymidine to an RNA precursor. Evidence from genetic, nutritional, and accumulation studies with the three mutants shows...
متن کاملAn unstable allele of the am locus of Neurospora crassa.
The mutant strain am126 was isolated, using the direct selection procedure, after nitrous acid mutagenesis. It produced neither measurable NADP-dependent glutamate dehydrogenase (GDH) nor immunologically cross-reacting material. That the am126 strain produced some form of GDH product was shown by the fact that it complemented several other am mutant strains. The GDH formed by complementation be...
متن کاملIsolation and characterization of low-kynureninase mutants of Neurospora crassa.
Two kynureninase activities are known in Neurospora crassa, one of which (kynureninase I) is inducible, the other (kynureninase II) being constitutive. A method is described for the isolation of low-kynureninase mutants of N. crassa. When grown on an inducer, the mutants show significantly less kynureninase I activity compared with wild type, whereas constitutive kynureninase II activity is una...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1979
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.137.3.1333-1339.1979